HGH (Human Growth Hormone) General Information
Human Growth Hormone or HGH treatment programs are intended for Men and Women over the age of 30 who have symptoms of Adult Growth Hormone Deficiency (AGHD). Human Growth Hormone (HGH) accelerates wound healing, healing and rehabilitation following injury, reverses the biological and physical effects of aging, maximizes physical performance, increases capacity for exercise and allows patients to live up to their genetic potential.

Manufacturers: Saizen | Geref (Seristim) | Nutropin | Genotropin

HGH can help qualified patients in the following ways...
• Reverses many symptoms of aging • Reverses muscle wasting
• 14% Reduction in weight and body fat after
six months (on average), without dieting
• 9% increase in lean muscle after six months, without exercise
• Increases energy level, endurance, and exercise capacity • Increases cardiac output and athletic performance
• Reduces stress and enhances immune system • Accelerated wound healing and skin regeneration
• Improves memory retention and cognitive functions • Improved recovery rate from athletic injury
• Improves vision • Achieve a younger, tighter, thicker skin
• Improves kidney function • Reverse osteoporosis, Improves sleep

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What are hormones?
Hormone, secretory substance carried from one gland or organ of the body via the bloodstream to more or less specific tissues, where it exerts some influence upon the metabolism of the target tissue. Normally, various hormones are produced and secreted by the endocrine glands (see endocrine system), including the pituitary, thyroid, parathyroids, adrenals, ovaries, testes, pancreatic islets, certain portions of the gastrointestinal tract, and the placenta, among the mammalian species. As lack of any one of them may cause serious disorders, many hormones are now produced synthetically and used in treatment where a deficiency exists. The hormones of the anterior pituitary include thyrotropin, adrenocorticotropic hormone, the gonadotropic hormones, and growth hormone; the posterior pituitary secretes antidiuretic hormone, prolactin, and oxytocin. The thyroids secrete thyroxine and calcitonin, and the parathyroids secrete parathyroid hormone. The adrenal medulla secretes epinephrine and norepinephrine while the cortex of the same gland releases aldosterone, corticosterone, cortisol, and cortisone. The ovaries primarily secrete estrogen and progesterone and the testes testosterone. The adrenal cortex, ovaries, and testes in fact produce at least small amounts of all of the steroid hormones. The islets of Langerhans in the pancreas secrete insulin, glucagon, and somatostatin. The kidneys also produce erythropoietin, which produces erythrocytes (red blood cells). The passage of chyme (see digestive system) from the stomach to the duodenum causes the latter to release secretin, which stimulates the flow of pancreatic juice. The duodenum can also be stimulated by the presence of fats in the chyme to secrete cholecystokinin, a hormone that stimulates the gall bladder to contract and release bile. There is evidence that the upper intestine secretes pancreatozymin, which enhances the amount of digestive enzymes in the pancreatic juice. In addition, the pyloric region of the stomach secretes gastrin, a hormone that increases the secretion of hydrochloric acid into the stomach. The placenta has been shown to secrete progesterone and chorionic gonadotropin. There is evidence that it even contains a substance similar to growth hormone. Insects have a unique hormonal system that includes ecdysone, a steroid that influences molting and metamorphosis, and juvenile hormone, needed for early development. Plants, too, have a hormonal system, which includes the auxins, the gibberellins, the cytokinins, and substances associated with the formation of flowers, tubers, bulbs, and buds. Ethylene is said to function as a hormone in plants, acting to hasten the ripening of fruits.

Growth Hormone levels?
The hormone most often said to affect aging and promote anti-aging is growth hormone. Growth hormone plays a pivotal but ³intermediate² role in the anti- aging process. The lack of this hormone doesn¹t bring about aging, but rather, the hormone lies in the middle of the aging cascade. Giving supplemental growth hormone to the aging body will restore some lost muscle mass and redistribute fat within the body, however it will not affect many other common aging changes, such as hair loss.

Researchers had long noticed that growth hormone hits its peak when the body goes through the rapid growth phase during adolescence. Hence the hormone¹s name. Most growth hormone secretion takes place in brief bursts called pulses that occur during the early hours of the deepest sleep. Indeed the old adage that you grow while you sleep appears to have a basis in fact.

Interestingly, growth hormone hangs around in the bloodstream for a very few minutes. However, this is long enough to stimulate its uptake into the liver, where it is converted into growth factors. Regulation of Growth Hormone is complex and comes under the control of many factors that regulate its release and function. Growth hormone declines with age in every animal species that has been tested to date. In humans, the amount of growth hormone after the age of twenty-one to thirty-one falls about 14 percent per decade, so that the total twenty-four-hour growth hormone production rate is reduced by half by the age of sixty.

Effects of Human Growth Hormone decline
The decline in human growth hormone is directly tied to the bulging, wrinkling, saggy, flabby, draggy creatures that we all sooner or later start to see in the mirror. Those of us with naturally lower amounts of hormone age much faster and more visibly that those of us who by reason of genes or high exercise level maintain a higher level of secretion for a longer period of time. The loss of the hormone with age is similar to that seen with menopause. And it has been given a similar name, the somatopause.

Health Tips About Using HGH
  • DO NOT EXCEED THE PRESCRIBED DOSAGE. Like most hormones, HGH is very potent. MORE IS NOT BETTER. If you are just starting HGH replacement therapy, you will be prescribed a small dose in the range of 0.1 to 0.3 mg per day. Remember that the goal of HGH replacement therapy is to restore your HGH production level.
  • WATCH FOR ADVERSE SIDE EFFECTS: Almost all adverse effects of HGH (water retention, sore muscles, numbness in the hands) are related to doses that are too high. If you are retaining water, ask your physician about lowering your dosage. Prolonged overproduction of HGH can cause serious side effects. This can occur in adults who have a hormonal disorder call acromegaly. The disorder is characterized by abnormal growth of the hands and feet. Soft tissue swelling of the hands and feet is often an early symptom, with patients noticing a change in ring or shoe size. If you notice any signs associated with acromegaly, consult your physician (preferably an endocrinologist).
  • EXERCISE: If you don't have an exercise program, start one. It doesn't have to be at a gym. Find a program that fits your life---walking, swimming, sports---anything that provides a reasonable workout several times a week. Studies have shown that HGH replacement therapy is more effective for people who exercise regularly.
  • MULTIPLE VITAMINS: Continue with a good multiple vitamin program that includes Vitamin C and Vitamin E.
  • SLEEP: Sleep is important to good health and it appears that several anti-aging hormones are produced at higher levels during sleep than during waking hours.
  • WATCH YOUR WEIGHT: HGH replacement therapy is not a diet program. Well it does tend to build muscle and reduce fat, many users find that they have an increased appetite.
  • SKIN AND SUN: When you are in the Sun, use sun protection. Use a good skin lotion morning and night. Consider using an "age-defying" lotion like that produced by Ponds or Oil of Olay.
  • DON'T SMOKE: If you have started HGH replacement therapy to look better, then don't smoke. Among other things, smoking makes your skin look older.
  • WATER: Drink plenty of water---every day!

What is a Gene?
Gene, the structural unit of inheritance in living organisms. A gene is, in essence, a segment of DNA that has a particular purpose, i.e., that codes for (contains the chemical information necessary for the creation of) a specific enzyme or other protein. The strands of DNA on which the genes occur are organized into chromosomes. The nucleus of each eukaryotic (nucleated) cell has a complete set of chromosomes and therefore a complete set of genes. Each gene provides a blueprint for the synthesis (via RNA) of enzymes and other proteins and specifies when these substances are to be made. Genes govern both the structure and metabolic functions of the cells, and thus of the entire organism and, when located in reproductive cells, they pass their information to the next generation. Chemically, each gene consists of a specific sequence of DNA building blocks called nucleotides. Each nucleotide is composed of three subunits: a nitrogen-containing compound, a sugar, and phosphoric acid. Geometrically, the gene is a double helix formed by the nucleotides. Gene loci are often interspersed with segments of DNA that do not code for proteins; these segments are termed "junk DNA. When junk DNA occurs within a gene, the coding portions are called exons and the noncoding (junk) portions are called introns. Junk DNA makes up 97% of the DNA in the human genome, and, despite its name, is necessary for the proper functioning of the genes. Each chromosome of each species has a definite number and arrangement of genes. Alteration of the number or arrangement of the genes can result in mutation. When the mutation occurs in the germ cells (egg or sperm), the change can be transmitted to the next generation. Mutations that affect somatic cells can result in certain cancers. The scientific study of inheritance is genetics. The genetic makeup of an organism with reference to its set of genetic traits is called its genotype. The interaction of the environment and the genotype produces the observable attributes of the organism, or its phenotype. The sum total of the genes contained in an organism's full set of chromosomes is termed the genome. Scientists are working toward identifying the location and function of each gene in the human genome. The decoding of the first free-living organism (a bacterium, Hemophilus influenza) was completed in 1995 by J. Craig Venter and Hamilton Smith.

What is Gene Therapy?
Gene therapy, the use of genes and the techniques of genetic engineering in the treatment of a genetic disorder or chronic disease. There are many techniques of gene therapy, all of them still in experimental stages. The two basic methods are called in vivo and ex vivo gene therapy. The in vivo method inserts genetically altered genes directly into the patient; the ex vivo method removes tissue from the patient, extracts the cells in question, and genetically alters them before returning them to the patient. The challenge of gene therapy lies in development of a means to deliver the genetic material into the nuclei of the appropriate cells, so that it will be reproduced in the normal course of cell division and have a lasting effect. One technique involves removing cells from a patient, fortifying them with healthy copies of the defective gene, and reinjecting them into the patient. Another involves inserting a gene into an inactivated or nonvirulent virus and using the virus's infective capabilities to carry the desired gene into the patient's cells. A liposome, a tiny fat-encased pouch that can traverse cell membranes, is also sometimes used to transport a gene into a body cell. Another approach employing liposomes, called chimeraplasty, involves the insertion of manufactured nucleic acid molecules (chimeraplasts) instead of entire genes to correct disease-causing gene mutations. Once inserted, the gene may produce an essential chemical that the patient's body cannot, remove or render harmless a substance or gene causing disease, or expose certain cells, especially cancerous cells, to attack by conventional drugs. Gene therapy was first used in humans in 1990 to treat a child with adenosine deaminase deficiency (ADA), a rare hereditary immune disorder (see immunity). It is hoped that gene therapy can be used to treat cancer, genetic diseases, and AIDS, but there are concerns that the immune system may attack cells treated by gene therapy, that the viral vectors could mutate and become virulent, or that altered genes might be passed to succeeding generations. In the United States, gene therapy techniques must be approved by the federal government. The Recombinant DNA Advisory Committee of the National Institutes of Health oversees gene therapy experiments. Like drugs, products must pass the requirements of the Food and Drug Administration. Gene therapy is a competitive and potentially lucrative field, and patents have been awarded for certain techniques.

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